CHLOROFORM AND HALOTHANE

Halogen bonded complexes between volatile anaesthetics (chloroform, halothane, enflurane, isoflurane) and formaldehyde: a theoretical study.

The structures and intermolecular interactions in the halogen bonded complexes of anaesthetics (chloroform, halothane, enflurane and isoflurane) with formaldehyde were studied by ab initio MP2 and CCSD(T) methods. The CCSD(T)/CBS calculated binding energies of these complexes are between -2.83 and -4.21 kcal mol(-1). The largest stabilization energy has been found for the C-Br···O bonded haloth...

Lack of mutagenic effect of halothane or chloroform on cultured cells using the azaguanine test system.

Halothane with and without nitrous oxide and chloroform alone were tested for mutagenic effects at the 8-azaguanine locus on the chromosomes of Chinese hamster lung fibroblast cells in culture. No significant numbers of mutations were found after 24 h exposures to 1-3% of these anaesthetics, or to 75% nitrous oxide.

Chloroform

It was perhaps fitting that Lieut.-Colonel Edward Lawrie, should signalise the year of his retirement from the post of R,esidenc\r Surgeon at Hyderabad by the publication of a volume on Chloroform, a subject with which he has been identified for many years past, and in defence of his views on which, and those of his master Syme, he has fought non sine gloria for many }7ears. The introduction to...

Chloroform

Electrochemical Behaviour of Nifedipine and Nitrendipine in Chloroform and Chloroform-Isopropanol Mixture

The electrochemical behavior of nifedipine (I), nitrendipine(II) and their photodegradation products has been studied by employing electrochemical techniques in chloroform and in 1:4 mixture of chloroform-isopropanol using piperidinium perchlorate (PPC) as supporting electrolyte. It has been shown that I and II undergo in a 4e, 4H+ irreversible reduction reaction, while the reduc...